Affinity Biosensors: Self Assembled Monolayers

Two model systems are common, one is based on thiols coupling (general formula R-SH) on Au(111) thin film with n-archetypal case of alkanethiols (both long and short-chain), and another on irreversible silane coupling to SiO2 thin films grown on Si substrates (Myhra 2004, Schreiber 2004).

Myhra S, Crossley A, Barsoum M W, Crystal chemistry from XPS analysis of carbide derived Mn+1 AXn (n=1) nano laminate compounds, Journal of physics and chemistry of solids Vol 63, pp 2063-2068 (2002)

Myhra S, A review of enabling technologies based on scanning probe microscopy relevant to bioanalysis, Biosensors and Bioelectronics Vol 19, pp 1345–1354 (2004)

Schreiber F, Structure and growth of self-assembling monolayers, Progress in Surface Science, Vol 65, Issues 5-8, pp 151-257 (2000)

Schreiber, F. Structure of thiol-based self-assembled monolayers, in Encyclopedia of Materials: Science and Technology, Elsevier, Oxford, pp.9323–9332 (2001)

Schreiber F, (Oxford Univ); Self assembled monolayers: from simple model system to biofunctionalized interfaces, J. of Physics: Condensed. Matter 16; R881–R900 (2004)


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