The largest source of human dioxin exposure comes though dietary intake of food of animal origin. Consequently, there are extensive monitoring programs in place to identify potential contamination entering into the food chain. This application note describes the use of the Thermo Scientific TSQ Quantum XLS Ultra GC-MS/MS as applied to high efficiency screening of PCDDs/PCDFs in feed and food samples at the levels of interest and the level of agreement with “gold standard” confirmatory analysis using GC-HRMS (Thermo Scientific DFS)
Determination of Fatty Acid Methyl Esters in Salmon Oil Using Automated Sample Preparation
Salmon oil is an excellent source of polyunsaturated omega-3 fatty acids. The two main fatty acids EPA and DHA have been identified as important health factors and are correlated with a normal function of the heart. This application note demonstrates the use of the Agilent 7696A Sample Prep WorkBench for derivatization and subsequent determination of both EPA and DHA from salmon oil capsules.
Analysis of Sugar Alcohol Excipients in Pharmaceuticals Using Rezex IEX HPLC Columns
Tablet formulations of most major drug products contain significant amounts of excipients in their formulations. Rezex ion exclusion HPLC columns are the solution for several published USP methodologies. The Rezex RPM (Pb+2) and RCM/RCU (Ca+2) phases will give you the selectivity needed while the short Rezex RPM 100 x 7.8 mm columns will help to increase throughput.
…………..Current European Union regulations permit the use of GC-MS/MS and bioassay techniques for screening dioxins and dioxin-like PCBs at the level of interest in feed and food samples.2 GC coupled with triple quadrupole MS is particularly suitable screening technique as isotope dilution is retained as well as the high selectivity of the MS/MS experiment……..