Gallium: characterisation by X-ray crystallography

Gallium(Ga) displays antitumor, antiresorptive, anti-inflammatory and immunosuppressive properties. Among all these properties, antitumor properties were the most extensively applied and have shown efficacy in treatment of Paget’s disease, myeloma and hypercalcemia in cases of malignancy. By contrast no clinical trials have been conducted in prevention or treatment of osteoporosis.

Although not as potent as platinum in vitro, the anticancer activity of Ga should not be ignored, but the schedule of administration still needs to be optimised and new compounds are now under clinical investigations.

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